SubtiBank SubtiBank
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2019-04-14 16:26:142025-05-23 16:57:41

title

yciC

zagA

description

zinc metallochaperone

zinc metallochaperone, ZTP activated GTPase A

locus

BSU03360

BSU_03360

function

zinc uptake

supply of zinc from [[protein|RpmE]] to [[protein|FolE]]

product

zinc metallochaperone

ZTP activated GTPase A

names

yciC

zagA

yciC

outlinks

bsu

BSU03360

BSU_03360

The protein

Protein family

cobW C-terminal domain (according to Swiss-Prot)

SIMIBI class G3E GTPase family (single member, according to UniProt)

References

12426338, 9811636, 18344368, 22517742, 18763711, 23406412, 27561249, 14696199

The protein

Catalyzed reaction/ biological activity

has GTPase and ZTPase activity [pubmed|31132310]

mobilization of zinc from [[protein|RpmE]] (after insertion of [[protein|RpmEB]] into the [SW|ribosome]), to provide it to [[protein|FolE]] [pubmed|31132310]

the interaction with FolE facilitates the supply of zinc to [[protein|FolE]] under conditions of zinc limitation [pubmed|31132310]

The protein

Kinetic information

KM for GTP: 40 µM [pubmed|31132310]

KM for ZTP: 36 µM [pubmed|31132310]

The protein

[SW|Domains]

CobW C-terminal domain (aa 259-374) (according to UniProt)

References

Reviews

31220391

References

Original publications

12426338, 9811636, 18344368, 22517742, 18763711, 23406412, 27561249, 14696199, 31132310